Cecil E. Hinshaw was president of William Penn College from 1944 to 1949. His administration would be one of the times when Quaker values were voiced and acted upon. His time at Penn is called, "The Holy Experiment".
Charles S. Ball served as president of William Penn College from 1949-1958. He had an advanced degree in theology and was the former president of Friends Bible College in Haviland, Kansas.
David M. Edwards was the sixth president of Penn College and the first alumnus of Penn to fill that role. After leaving Penn he would go on to become president of Earlham College and Friends University.